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Article

Hepatitis B viral surface mutations in patients with adefovir resistant chronic hepatitis B with A181T/V polymerase mutations.

Journal of Korean medical science - 1 Feb 2010

Kim Jeong Han, Jung Young Kul, Joo Moon Kyung, Kim Ji Hoon, Yim Hyung Joon, Park Jong-Jae, Kim Jae Seon, Bak Young-Tae, Yeon Jong Eun, Byun Kwan Soo

Abstract excerpt

The hepatitis B virus (HBV) polymerase gene has overlapping reading frames with surface genes, which allows to alter the amino acid codon of the surface genes. In adefovir (ADV) treated chronic hepatitis B patients carrying rtA181T/rtA181V mutations, overlap with surface gene mutations such as sW172stop/sL173F has been reported. However, the clinical consequences of such surface mutations have not been...

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Identifiers

PMID: 20119580
DOI: 10.3346/jkms.2010.25.2.257
PMCID: PMC2811294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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