Article
Serotonin transporter protein (SLC6A4) allele and haplotype frequencies and linkage disequilibria in African- and European-American and Japanese populations and in alcohol-dependent subjects.
Human genetics - 1 Dec 1997
Gelernter J, Kranzler H, Cubells J F
Abstract excerpt
The SLC6A4 locus encodes the serotonin transporter, which in turn mediates the synaptic inactivation of the neurotransmitter serotonin. Two PCR-formatted polymorphisms at this locus have been described, the first of which is a variable number tandem repeat located in exon 2, and the second a repe...
Topics
- Alcoholism
- Alleles
- Asian People
- Black People
- Carrier Proteins
- Europe
- Female
- Gene Frequency
- Haplotypes
- Humans
- Japan
- Linkage Disequilibrium
- Male
- Membrane Glycoproteins
- Membrane Transport Proteins
- Nerve Tissue Proteins
- Polymorphism, Genetic
- Serotonin Plasma Membrane Transport Proteins