Article
Behavioral phenotyping of a transgenic Caenorhabditis elegans expressing neuronal amyloid-beta.
Journal of Alzheimer's disease : JAD - 1 Jan 2010
Dosanjh Laura E, Brown Marishka K, Rao Gautam, Link Christopher D, Luo Yuan
Abstract excerpt
Alzheimer's disease (AD) is rapidly reaching epidemic proportions in the United States, currently affecting more than 5 million individuals and predicted to affect 14 million by 2050. Despite a general consensus that the amyloid-beta (Abeta) protein plays a significant role in disease progression, the underlying pathology of the disease is not entirely clear. Caenorhabditis elegans is a simple organism that has...
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