Article
Receptor activity-modifying protein 1 increases baroreflex sensitivity and attenuates Angiotensin-induced hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Mar 2010
Sabharwal Rasna, Zhang Zhongming, Lu Yongjun, Abboud Francois M, Russo Andrew F, Chapleau Mark W
Abstract excerpt
Calcitonin gene-related peptide (CGRP) is a powerful vasodilator that interacts with the autonomic nervous system. A subunit of the CGRP receptor complex, receptor activity-modifying protein 1 (RAMP1), is required for trafficking of the receptor to the cell surface and high-affinity binding to CG...
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