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Article

Design and application of antibody cysteine variants.

Bioconjugate chemistry - 17 Feb 2010

Voynov Vladimir, Chennamsetty Naresh, Kayser Veysel, Wallny Hans-Joachim, Helk Bernhard, Trout Bernhardt L

Abstract excerpt

Antibodies are multidomain proteins that are extensively used as a research tool in molecular biology and as therapeutics in medicine. In many cases, antibodies are engineered to contain surface cysteines for the site-specific conjugation of payloads. These antibodies can serve as payload vehicles in targeting a diseased cell to which the conjugated molecules exercise their activity. Here, we design and analyze a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20092294
DOI: 10.1021/bc900509s

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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