Article
Identification of 167 polymorphisms in 88 genes from candidate neurodegeneration pathways.
Gene - 1 Oct 1999
Emahazion T, Jobs M, Howell W M, Siegfried M, Wyöni P I, Prince J A, Brookes A J
Abstract excerpt
Catalogs of intra-gene polymorphisms are needed to facilitate wide-ranging candidate gene-based association studies in common complex diseases. With this in mind, we have scanned multiple alignments of expressed sequence tags and of genomic DNA sequences (PCR products from four to eight unrelated individuals) to find polymorphisms in 195 genes putatively involved in neurodegenerative illness (including components...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
