Article
Functional variation in the androgen-receptor gene is associated with visceral adiposity and blood pressure in male adolescents.
Hypertension (Dallas, Tex. : 1979) - 1 Mar 2010
Pausova Zdenka, Abrahamowicz Michal, Mahboubi Amel, Syme Catriona, Leonard Gabriel T, Perron Michel, Richer Louis, Veillette Suzanne, Gaudet Daniel, Paus Tomas
Abstract excerpt
Intra-abdominal accumulation of fat is a hallmark of male body-fat distribution and a major risk factor for hypertension. Sympathoactivation may be one of the mechanisms linking intra-abdominal obesity to hypertension. The aim of the present study was to investigate whether a functional variation in the androgen-receptor gene (AR, a variable number of CAG repeats in exon 1) is associated with intra-abdominal...
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