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Article

Evidence for molecular mimicry between human T cell epitopes in rotavirus and pancreatic islet autoantigens.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2010

Honeyman Margo C, Stone Natalie L, Falk Ben A, Nepom Gerald, Harrison Leonard C

Abstract excerpt

In type 1 diabetes, insulin-producing beta cells in the islets of the pancreas are destroyed by autoreactive T cells. Rotavirus (RV) has been implicated in the pathogenesis of type 1 diabetes. Peptides in VP7, a major immunogenic protein of RV, have high sequence similarity to T cell epitope pept...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20083660
DOI: 10.4049/jimmunol.0900709

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20083660-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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