Article
IL-1B polymorphism in association with initial intravenous immunoglobulin treatment failure in Taiwanese children with Kawasaki disease.
Circulation journal : official journal of the Japanese Circulation Society - 1 Mar 2010
Weng Ken-Pen, Hsieh Kai-Sheng, Ho Tsyr-Yuh, Huang Shih-Hui, Lai Chung-Ren, Chiu Yi-Ten, Huang Shih-Chen, Lin Chu-Chuan, Hwang Yu-Tung, Ger Luo-Ping
Abstract excerpt
BACKGROUND: Approximately 8-38% of children with Kawasaki disease (KD) will have persistent or recrudescent fever after initial intravenous immunoglobulin (IVIG) treatment and are at increased risk for development of coronary artery abnormalities. Using genetic markers may be helpful to identify the high-risk group of IVIG-resistant patients for aggressive treatment. The aim of this study was to evaluate the...
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