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Article

The alpha2delta subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for function.

Proceedings of the National Academy of Sciences of the United States of America - 26 Jan 2010

Davies Anthony, Kadurin Ivan, Alvarez-Laviada Anita, Douglas Leon, Nieto-Rostro Manuela, Bauer Claudia S, Pratt Wendy S, Dolphin Annette C

Abstract excerpt

Voltage-gated calcium channels are thought to exist in the plasma membrane as heteromeric proteins, in which the alpha1 subunit is associated with two auxiliary subunits, the intracellular beta subunit and the alpha(2)delta subunit; both of these subunits influence the trafficking and properties...

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Source

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Identifiers

PMID: 20080692
DOI: 10.1073/pnas.0908735107
PMCID: PMC2824380

Genes

GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20080692-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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