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Article

The calcium channel alpha2delta-2 subunit partitions with CaV2.1 into lipid rafts in cerebellum: implications for localization and function.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 23 Aug 2006

Davies Anthony, Douglas Leon, Hendrich Jan, Wratten Jack, Tran Van Minh Alexandra, Foucault Isabelle, Koch Dietlind, Pratt Wendy S, Saibil Helen R, Dolphin Annette C

Abstract excerpt

The accessory alpha2delta subunits of voltage-gated calcium channels are highly glycosylated transmembrane proteins that interact with calcium channel alpha1 subunits to enhance calcium currents. We compared the membrane localization and processing of native cerebellar alpha2delta-2 subunits with alpha2delta-2 stably expressed in tsA-201 cells. We identified that alpha2delta-2 is completely concentrated in...

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Identifiers

PMID: 16928863
DOI: 10.1523/JNEUROSCI.2764-06.2006
PMCID: PMC6674382

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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