Article
Variant CJD infection in the spleen of a neurologically asymptomatic UK adult patient with haemophilia.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Mar 2010
Peden A, McCardle L, Head M W, Love S, Ward H J T, Cousens S N, Keeling D M, Millar C M, Hill F G H, Ironside J W
Abstract excerpt
SUMMARY: All UK patients with bleeding disorders treated with any UK-sourced pooled factor concentrates between 1980 and 2001 have been informed that they may be at an increased risk of infection with variant Creutzfeldt-Jakob disease (vCJD). We describe a study to detect disease-associated, protease-resistant prion protein (PrP(res)) in 17 neurologically aymptomatic patients with haemophilia considered to be at...
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