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Article

Variant Creutzfeldt-Jakob disease: prion protein genotype analysis of positive appendix tissue samples from a retrospective prevalence study.

BMJ (Clinical research ed.) - 20 May 2006

Ironside James W, Bishop Matthew T, Connolly Kelly, Hegazy Doha, Lowrie Suzanne, Le Grice Margaret, Ritchie Diane L, McCardle Linda M, Hilton David A

Abstract excerpt

OBJECTIVE: To perform prion protein gene (PRNP) codon 129 analysis in DNA extracted from appendix tissue samples that had tested positive for disease associated prion protein. DESIGN: Reanalysis of positive cases identified in a retrospective anonymised unlinked prevalence study of variant Creutzfeldt-Jakob disease (vCJD) in the United Kingdom. STUDY SAMPLES: Three positive appendix tissue samples out of 12,674...

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Identifiers

PMID: 16606639
DOI: 10.1136/bmj.38804.511644.55
PMCID: PMC1463905

Genes

PRNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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