Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Estimating CDKN2A carrier probability and personalizing cancer risk assessments in hereditary melanoma using MelaPRO.

Cancer research - 15 Jan 2010

Wang Wenyi, Niendorf Kristin B, Patel Devanshi, Blackford Amanda, Marroni Fabio, Sober Arthur J, Parmigiani Giovanni, Tsao Hensin

Abstract excerpt

Personalized cancer risk assessment remains an essential imperative in postgenomic cancer medicine. In hereditary melanoma, germline CDKN2A mutations have been reproducibly identified in melanoma-prone kindreds worldwide. However, genetic risk counseling for hereditary melanoma remains clinically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Penetrance
Share to Algorithms
Share to Genes, p16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Melanoma

Share to Models, Genetic

Share to Reproducibility of Results

Share to Risk Assessment

Source

Open in PubMed Open full text

Identifiers

PMID: 20068151
DOI: 10.1158/0008-5472.CAN-09-2653
PMCID: PMC2947347

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20068151-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Estimating CDKN2A carrier probability and personalizing cancer risk assessments in hereditary melanoma using MelaPRO.PMID 20068151Read ↗

Melanoma genetics: an update on risk-associated genes.Semantic proximity Read ↗

Unveiling the genetic landscape of hereditary melanoma: From susceptibility to surveillance.Semantic proximity Read ↗

CDKN2A genetic testing in melanoma-prone families in Sweden in the years 2015-2020: implications for novel national recommendations.Semantic proximity Read ↗

Bioinformatic and Machine Learning Applications in Melanoma Risk Assessment and Prognosis: A Literature Review.Semantic proximity Read ↗

MELPREDICT: a logistic regression model to estimate CDKN2A carrier probability.Semantic proximity Read ↗

Genetic testing for melanoma predisposition: current challenges.Semantic proximity Read ↗

Recommendations for Primary Prevention of Skin MelanomaSemantic proximity Read ↗

Melanoma risk prediction based on a polygenic risk score and clinical risk factors.Semantic proximity Read ↗

Genetics versus clinical risk scores for melanoma prediction.Semantic proximity Read ↗

Family-based whole-exome sequencing identifies rare variants potentially related to cutaneous melanoma predisposition in Brazilian melanoma-prone families.Semantic proximity Read ↗

Genetic markers for characterization and prediction of prognosis of melanoma subtypes: a 2021 update.Semantic proximity Read ↗

Retrospective study of germline variants in patients with hereditary melanoma study criteria in a real clinical practice setting.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.