Article
Nuclear-localized subtype of end-binding 1 protein regulates spindle organization in Arabidopsis.
Journal of cell science - 1 Feb 2010
Komaki Shinichiro, Abe Tatsuya, Coutuer Silvie, Inzé Dirk, Russinova Eugenia, Hashimoto Takashi
Abstract excerpt
End-binding 1 (EB1) proteins are evolutionarily conserved plus-end-tracking proteins that localize to growing microtubule plus ends where they regulate microtubule dynamics and interactions with intracellular targets. Animal EB1 proteins have acidic C-terminal tails that might induce an autoinhibitory conformation. Although EB1 proteins with the same structural features occur in plants (EB1a and EB1b in...
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