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Article

Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults.

Haematologica - 1 Jan 2010

Gorello Paolo, La Starza Roberta, Varasano Emanuela, Chiaretti Sabina, Elia Loredana, Pierini Valentina, Barba Gianluca, Brandimarte Lucia, Crescenzi Barbara, Vitale Antonella, Messina Monica, Grammatico Sara, Mancini Marco, Matteucci Caterina, Bardi Antonella, Guarini Anna, Martelli Massimo Fabrizio, Foà Robin, Mecucci Cristina

Abstract excerpt

BACKGROUND: Molecular lesions in T-cell acute lymphoblastic leukemias affect regulators of cell cycle, proliferation, differentiation, survival and apoptosis in multi-step pathogenic pathways. Full genetic characterization is needed to identify events concurring in the development of these leukem...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20065082
DOI: 10.3324/haematol.2009.010413
PMCID: PMC2805748

Genes

NUP214
CDKN2A
FNBP1
GRIK2
MYB
NF1
TAL1
TLX3
USP20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20065082-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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