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Article

The DNA methylome of glioblastoma multiforme.

Neurobiology of disease - 1 Jul 2010

Martinez Ramon, Esteller Manel

Abstract excerpt

Glioblastoma multiforme (GBM) is the most frequent brain tumor in adults. This lethal cancer is a challenge in neuro-oncology since patients almost invariably succumb to the disease. Intensive molecular studies have revealed a variety of deregulated genetic pathways involved in DNA repair, apoptosis, cell migration, angiogenesis and cell cycle. Recent investigation of epigenetic lesions in GBM have led to a more...

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Source

Identifiers

PMID: 20064612
DOI: 10.1016/j.nbd.2009.12.030

Genes

MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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