Article
Factors predicting outcome of total thyroidectomy in young patients with multiple endocrine neoplasia type 2: a nationwide long-term follow-up study.
World journal of surgery - 1 Apr 2010
Schreinemakers Jennifer M J, Vriens Menno R, Valk Gerlof D, de Groot Jan-Willem B, Plukker John T, Bax Klaas M A, Hamming Jaap F, van der Luijt Rob B, Aronson Daniel C, Borel Rinkes Inne H M
Abstract excerpt
BACKGROUND Multiple endocrine neoplasia type 2 (MEN 2) is caused by a RET mutation in chromosome 10. All MEN 2 patients develop medullary thyroid carcinoma (MTC). The age-related risk of MTC is associated with the type of RET mutation. Our aim was to identify prognostic factors associated with recurrent MTC in MEN 2 patients. METHODS In a nationwide case-control study, all patients who underwent total...
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