Article
Association between 5-hydroxytryptamine transporter gene-linked polymorphic region and smoking behavior in Chinese males.
Chinese medical journal - 20 Jun 2009
Chu Shui-Lian, Xiao Dan, Wang Chen, Jing Hang
Abstract excerpt
BACKGROUND: Tobacco use is the major risk factor for numerous health problems. However, only 5% of smokers can successfully quit without therapy owing to the highly addictive properties of nicotine. The serotoninergic system may be involved in smoking behavior because nicotine increases brain serotonin secretion, nicotine withdrawal decreases serotonin levels, and a selective serotonin reuptake inhibitor...
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