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Article

Role of glycogen synthase kinase 3 (GSK-3) in innate immune response of human immature dendritic cells to Aspergillus fumigatus.

Medical mycology - 1 Jun 2010

Spinnler Katrin, Mezger Markus, Steffens Michael, Sennefelder Helga, Kurzai Oliver, Einsele Hermann, Loeffler Juergen

Abstract excerpt

Dysregulation of the Th1/Th2 cytokine balance and a switch to a Th2 immune response contribute to the development of and the unfavorable outcome from invasive aspergillosis (IA). We explore in this paper the role of glycogen synthase kinase 3 (GSK-3) in human immature dendritic cells (iDCs) relative to infection caused by A. fumigatus by the use of GSK-3 inhibitors (LiCl, SB415286) and RNA interference...

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Identifiers

PMID: 20055739
DOI: 10.3109/13693780903420625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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