Article
Pathogenesis, risk assessment and prevention of type 2 diabetes mellitus.
Obesity facts - 1 Jan 2008
Joost Hans-Georg
Abstract excerpt
Type 2 diabetes mellitus is a complex, polygenic disease with a heterogeneous pathophysiology, mainly characterised by obesity-associated insulin resistance and a progressive failure of pancreatic beta-cells. Predominant risk factors for its development are abdominal obesity and age; other factors that augment the individual disease risk independent of obesity are the nutritional pattern (low consumption of...
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