Article
Cooperative effect of serum 25-hydroxyvitamin D concentration and a polymorphism of transforming growth factor-beta1 gene on the prevalence of vertebral fractures in postmenopausal osteoporosis.
Journal of bone and mineral metabolism - 1 Jul 2010
Mori Seijiro, Fuku Noriyuki, Chiba Yuko, Tokimura Fumiaki, Hosoi Takayuki, Kimbara Yoshiyuki, Tamura Yoshiaki, Araki Atsushi, Tanaka Masashi, Ito Hideki
Abstract excerpt
A T869-->C polymorphism of the transforming growth factor-beta1 (TGF-beta1) gene is reported to be associated with genetic susceptibility to both osteoporosis and vertebral fractures. A low serum 25-hydroxyvitamin D [25(OH)D] level is known to be associated with a higher risk for hip fracture. Th...
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