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Article

Synthesis and Therapeutic Applications of Iminosugars in Cystic Fibrosis.

International journal of molecular sciences - 9 May 2020

Esposito Anna, D'Alonzo Daniele, Fenza Maria De, Gregorio Eliana De, Tamanini Anna, Lippi Giuseppe, Dechecchi Maria Cristina, Guaragna Annalisa

Abstract excerpt

Iminosugars are sugar analogues endowed with a high pharmacological potential. The wide range of biological activities exhibited by these glycomimetics associated with their excellent drug profile make them attractive therapeutic candidates for several medical interventions. The ability of iminosugars to act as inhibitors or enhancers of carbohydrate-processing enzymes suggests their potential use as therapeutics...

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Identifiers

PMID: 32397443
DOI: 10.3390/ijms21093353
PMCID: PMC7247015

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