Article
Glucosidase inhibitors for treatment of HIV-1 infection.
AIDS research and human retroviruses - 1 Feb 1992
Ratner L
Abstract excerpt
The HIV-1 envelope protein is a glycoprotein composed of 120 kD and 41 kD subunits. It contains 30-38 potential asparagine-linked glycosylation sites which have been shown to play a role in CD4 binding, virus uptake, and cytopathogenicity. Several inhibitors of oligosaccharide attachment or modif...
Topics
- Acquired Immunodeficiency Syndrome
- Amino Acid Sequence
- Antiviral Agents
- Carbohydrate Sequence
- Gene Products, env
- Glucosidases
- Glycosylation
- HIV-1
- Humans
- Molecular Sequence Data
- Mutation
- Protein Processing, Post-Translational