Article
HIV-1 subtype and viral tropism determination for evaluating antiretroviral therapy options: an analysis of archived Kenyan blood samples.
BMC infectious diseases - 30 Dec 2009
Lihana Raphael W, Khamadi Samoel A, Lwembe Raphael M, Kinyua Joyceline G, Muriuki Joseph K, Lagat Nancy J, Okoth Fredrick A, Makokha Ernest P, Songok Elijah M
Abstract excerpt
BACKGROUND: Infection with HIV-1 is characterized by genetic diversity such that specific viral subtypes are predominant in specific geographical areas. The genetic variation in HIV-1 pol and env genes is responsible for rapid development of resistance to current drugs. This variation has influen...
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