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Article

HIV-1 subtype and viral tropism determination for evaluating antiretroviral therapy options: an analysis of archived Kenyan blood samples.

BMC infectious diseases - 30 Dec 2009

Lihana Raphael W, Khamadi Samoel A, Lwembe Raphael M, Kinyua Joyceline G, Muriuki Joseph K, Lagat Nancy J, Okoth Fredrick A, Makokha Ernest P, Songok Elijah M

Abstract excerpt

BACKGROUND: Infection with HIV-1 is characterized by genetic diversity such that specific viral subtypes are predominant in specific geographical areas. The genetic variation in HIV-1 pol and env genes is responsible for rapid development of resistance to current drugs. This variation has influenced disease progression among the infected and necessitated the search for alternative drugs with novel targets. Though...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20040114
DOI: 10.1186/1471-2334-9-215
PMCID: PMC2804586

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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