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Article

Mutational analysis of parkin and PINK1 in multiple system atrophy.

Neurobiology of aging - 1 Mar 2011

Brooks Janet A, Houlden Henry, Melchers Anna, Islam Ansha J, Ding Jinhui, Li Abi, Paudel Reema, Revesz Tamas, Holton Janice L, Wood Nick, Lees Andrew, Singleton Andrew B, Scholz Sonja W

Abstract excerpt

Multiple system atrophy (MSA) and Parkinson's disease (PD) are progressive neurodegenerative disorders with overlapping clinical, biochemical and genetic features. To test the hypothesis that the PD genes parkin and PINK1 also play a role in the pathogenesis of MSA, we performed a mutational screening study involving 87 pathologically proven MSA cases. In parkin we identified eight sequence variants and four...

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Identifiers

PMID: 20034704
DOI: 10.1016/j.neurobiolaging.2009.11.020
PMCID: PMC3934211

Genes

PINK1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Mutational analysis of parkin and PINK1 in multiple system atrophy.PMID 20034704Read ↗

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PARKIN-coding polymorphisms are not associated with Parkinson's disease in a population from northeastern Mexico.Semantic proximity Read ↗

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