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Article

Social- and behavioral-specific genetic effects on blood pressure traits: the Strong Heart Family Study.

Circulation. Cardiovascular genetics - 1 Aug 2009

Franceschini Nora, Rose Kathryn M, Storti Kristi L, Rutherford Sue, Voruganti V Saroja, Laston Sandy, Göring Harald H H, Dyer Thomas D, Umans Jason G, Lee Elisa T, Best Lyle G, Fabsitz Richard R, Cole Shelley A, MacCluer Jean W, North Kari E

Abstract excerpt

BACKGROUND: Population studies have demonstrated an important role of social, behavioral, and environmental factors in blood pressure (BP) levels. Accounting for the genetic interaction of these factors may help to identify common BP susceptibility alleles. METHODS AND RESULTS: We studied the interaction of additive genetic effects and behavioral (physical activity, smoking, alcohol use) and socioeconomic...

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Identifiers

PMID: 20031612
DOI: 10.1161/CIRCGENETICS.109.853630
PMCID: PMC2742382

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