Article
[Future perspectives of immunotherapy against ALS].
Rinsho shinkeigaku = Clinical neurology - 1 Nov 2009
Urushitani Makoto
Abstract excerpt
Emerging evidence suggests that misfolded proteins in the various neurodegenerative diseases can be targets for immunotherapy including vaccination antibody therapy. To date, vaccination strategies have been shown to be effective in Alzheimer's disease, Parkinson's disease, Huntington's disease and Prion disease. Interestingly, the subcellular localization of the target proteins varies, including cytosol,...
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