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Syndactyly lethal: new mutation with multiple malformations occurring in Sprague Dawley rats.

Congenital anomalies - 1 Dec 2009

Fujii Sakiko, Yabe Kaoru, Kimura Yuki, Ito Yukie, Rokukawa Masumi, Furukawa Masatoshi, Ito Kouta, Matsuura Masao, Kiguchi Masao

Abstract excerpt

We previously found newborns exhibiting syndactyly of both fore- and hindlimbs in a litter from a pair of Sprague Dawley rats. Continuous breeding of the parental animals yielded pups with the same anomaly in following litters, suggesting that the syndactyly was genetic in origin. In the present study, as all the syndactylous pups died on postnatal day 0, we conducted genetic analyses using 30 phenotypically...

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PMID: 20021486
DOI: 10.1111/j.1741-4520.2009.00244.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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