Article
Polydactyly lethal: a new mutant spontaneously occurring in the FPL strain of rats.
The Journal of heredity - 1 Jan 2000
Aoyama H, Fujii S, Teramoto S, Shirasu Y
Abstract excerpt
A new mutant gene that causes preaxial polydactyly in the hindlimbs was found in the strain of rats with fused pulmonary lobes (fpl). Genetic analysis has revealed that the new mutation is inherited as an autosomal recessive trait and is not closely linked with the fpl gene. Since homozygous mutants die within the first 2 days after birth, the mutant gene was named polydactyly lethal, gene symbol pl. A test for...
Topics
- Alleles
- Animals
- Crosses, Genetic
- Female
- Foot Deformities
- Genes, Lethal
- Genes, Recessive
- Genetic Linkage
- Male
- Pedigree
- Rats
- Rats, Mutant Strains