Article
Evidence of uneven selective pressure on different subsets of the conserved human genome; implications for the significance of intronic and intergenic DNA.
BMC genomics - 16 Dec 2009
Davidson Scott, Starkey Andrew, MacKenzie Alasdair
Abstract excerpt
BACKGROUND: Human genetic variation produces the wide range of phenotypic differences that make us individual. However, little is known about the distribution of variation in the most conserved functional regions of the human genome. We examined whether different subsets of the conserved human genome have been subjected to similar levels of selective constraint within the human population. We used set theory and...
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