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Article

Effects of natural selection on interpopulation divergence at polymorphic sites in human protein-coding Loci.

Genetics - 1 Jul 2005

Hughes Austin L, Packer Bernice, Welch Robert, Bergen Andrew W, Chanock Stephen J, Yeager Meredith

Abstract excerpt

To develop new strategies for searching for genetic associations with complex human diseases, we analyzed 2784 single-nucleotide polymorphisms (SNPs) in 396 protein-coding genes involved in biological processes relevant to cancer and other complex diseases, with respect to gene diversity within samples of individuals representing the three major historic human populations (African, European, and Asian) and with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15911586
DOI: 10.1534/genetics.104.037077
PMCID: PMC1242184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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