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Zygote Arrest 1 (Zar1) Is an Evolutionarily Conserved Gene Expressed in Vertebrate Ovaries1

1 Sept 2003

Abstract excerpt

Zygote arrest 1 (ZAR1) is an ovary-specific maternal factor that plays essential roles during the oocyte-to-embryo transition. In mice, the Zar1 mRNA is detected as a 1.4-kilobase (kb) transcript that is synthesized exclusively in growing oocytes. To further understand the functions of ZAR1, we have cloned the orthologous Zar1 cDNA and/or genes for mouse, rat, human, frog, zebrafish, and pufferfish. The entire...

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PMID: 12773403
DOI: 10.1095/biolreprod.103.016022

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