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Article

Alpha1-syntrophin mutations identified in sudden infant death syndrome cause an increase in late cardiac sodium current.

Circulation. Arrhythmia and electrophysiology - 1 Dec 2009

Cheng Jianding, Van Norstrand David W, Medeiros-Domingo Argelia, Valdivia Carmen, Tan Bi-hua, Ye Bin, Kroboth Stacie, Vatta Matteo, Tester David J, January Craig T, Makielski Jonathan C, Ackerman Michael J

Abstract excerpt

BACKGROUND: Sudden infant death syndrome (SIDS) is a leading cause of death during the first 6 months after birth. About 5% to 10% of SIDS may stem from cardiac channelopathies such as long-QT syndrome. We recently implicated mutations in alpha1-syntrophin (SNTA1) as a novel cause of long-QT synd...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20009079
DOI: 10.1161/CIRCEP.109.891440
PMCID: PMC2810855

Genes

SNTA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20009079-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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