Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ExsD inhibits expression of the Pseudomonas aeruginosa type III secretion system by disrupting ExsA self-association and DNA binding activity.

Journal of bacteriology - 1 Mar 2010

Brutinel Evan D, Vakulskas Christopher A, Yahr Timothy L

Abstract excerpt

Pseudomonas aeruginosa utilizes a type III secretion system (T3SS) to damage eukaryotic host cells and evade phagocytosis. Transcription of the T3SS regulon is controlled by ExsA, a member of the AraC/XylS family of transcriptional regulators. ExsA-dependent transcription is coupled to type III secretory activity through a cascade of three interacting proteins (ExsC, ExsD, and ExsE). Genetic data suggest that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Pseudomonas aeruginosa

Share to Recombinant Fusion Proteins

Share to Repressor Proteins

Share to Trans-Activators

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 20008065
DOI: 10.1128/JB.01457-09
PMCID: PMC2832532

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ExsD inhibits expression of the Pseudomonas aeruginosa type III secretion system by disrupting ExsA self-association and DNA binding activity.PMID 20008065Read ↗

ExsD is a negative regulator of the Pseudomonas aeruginosa type III secretion regulon.Semantic proximity Read ↗

PsrA is a positive transcriptional regulator of the type III secretion system in Pseudomonas aeruginosa.Semantic proximity Read ↗

The distal ExsA-binding site in Pseudomonas aeruginosa type III secretion system promoters is the primary determinant for promoter-specific properties.Semantic proximity Read ↗

Effector ExoU from the type III secretion system is an important modulator of gene expression in lung epithelial cells in response to Pseudomonas aeruginosa infection.Semantic proximity Read ↗

Quorum sensing employs a dual regulatory mechanism to repress T3SS gene expressionSemantic proximity Read ↗

Cloning and sequence analysis of a trans-regulatory locus required for exoenzyme S synthesis in Pseudomonas aeruginosa.Semantic proximity Read ↗

Nutritional Regulation of the Sae Two-Component System by CodY in Staphylococcus aureusSemantic proximity Read ↗

Modulation of bacterial Type III secretion system by a spermidine transporter dependent signaling pathway.Semantic proximity Read ↗

Construction and characterization of chromosomal insertional mutations of the Pseudomonas aeruginosa exoenzyme S trans-regulatory locus.Semantic proximity Read ↗

Isolation of a Membrane Protein Complex for Type VII Secretion in Staphylococcus aureus.Semantic proximity Read ↗

Pseudomonas aeruginosa exoenzyme Y directly bundles actin filaments.Semantic proximity Read ↗

ExoS effector in Pseudomonas aeruginosa Hyperactive Type III secretion system mutant promotes enhanced Plasma Membrane Rupture in Neutrophils.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.