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Article

Caught in the middle: the role of Bag3 in disease.

The Biochemical journal - 14 Dec 2009

McCollum Andrea K, Casagrande Giovanna, Kohn Elise C

Abstract excerpt

Bag3 is a Bag family co-chaperone that regulates the ATPase activity of Hsp70 (heat-shock protein 70) chaperones. Recent studies have demonstrated that Bag3 can initiate macroautophagy in co-operation with small heat-shock protein HspB8. In this issue of the Biochemical Journal, Fuchs and co-work...

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Identifiers

PMID: 20001957
DOI: 10.1042/BJ20091739
PMCID: PMC7291699

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20001957-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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The stress-inducible HspB8-Bag3 complex induces the eIF2alpha kinase pathway: implications for protein quality control and viral factory degradation?Semantic proximity Read ↗

Therapeutic targeting of BAG3: considering its complexity in cancer and heart disease.Semantic proximity Read ↗

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