Article
Genotyping of Trypanosoma cruzi: systematic selection of assays allowing rapid and accurate discrimination of all known lineages.
The American journal of tropical medicine and hygiene - 1 Dec 2009
Lewis Michael D, Ma Jonathan, Yeo Matthew, Carrasco Hernán J, Llewellyn Martin S, Miles Michael A
Abstract excerpt
Trypanosoma cruzi, the agent of Chagas disease, can be subdivided into six discrete typing units (DTUs), TcI, TcIIa, TcIIb, TcIIc, TcIId or TcIIe, each having distinct epidemiologically important features. Dozens of genetic markers are available to determine the DTU to which a T. cruzi isolate belongs, but there is no consensus on which should be used. We selected five assays: three polymerase chain reaction...
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