Article
Multilocus polymerase chain reaction restriction fragment--length polymorphism genotyping of Trypanosoma cruzi (Chagas disease): taxonomic and clinical applications.
The Journal of infectious diseases - 1 May 2007
Rozas Marlene, De Doncker Simonne, Adaui Vanessa, Coronado Ximena, Barnabé Christian, Tibyarenc Michel, Solari Aldo, Dujardin Jean-Claude
Abstract excerpt
BACKGROUND: Trypanosoma cruzi, the agent of Chagas disease, is subdivided into 6 discrete typing units (DTUs); their identification is important to understand clinical pleomorphism and track sylvatic DTUs that might (re-)invade domestic foci of the disease and jeopardize the running control programs. METHODS: The genetic polymorphism of 12 loci was analyzed by multilocus polymerase chain reaction restriction...
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