Article
Genetic control of the innate immune response to Borrelia hermsii influences the course of relapsing fever in inbred strains of mice.
Infection and immunity - 1 Feb 2010
Benoit Vivian M, Petrich Annett, Alugupalli Kishore R, Marty-Roix Robin, Moter Annette, Leong John M, Boyartchuk Victor L
Abstract excerpt
Host susceptibility to infection is controlled in large measure by the genetic makeup of the host. Spirochetes of the genus Borrelia include nearly 40 species of vector-borne spirochetes that are capable of infecting a wide range of mammalian hosts, causing Lyme disease and relapsing fever. Relapsing fever is associated with high-level bacteremia, as well as hematologic manifestations, such as thrombocytopenia...
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