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Article

Acute myeloid leukaemia relapsing following interleukin-2 treatment expresses the alpha chain of the interleukin-2 receptor.

British journal of haematology - 1 Jan 1991

Macdonald D, Jiang Y Z, Swirsky D, Vulliamy T, Morilla R, Bungey J, Barrett A J

Abstract excerpt

Immunotherapy with recombinant human Interleukin-2 (rhIL-2) was given to nine patients in first complete remission from acute myeloid leukaemia (AML). Five patients relapsed. The median time to relapse after commencing rhIL-2 was 26 weeks (range 2-44). Four patients were studied at relapse. The morphological and cytochemical features at relapse and presentation were similar. Cytogenetic analysis at relapse in...

Topics

Adult
Female
Gene Rearrangement
Humans
Interleukin-2
Leukemia, Myeloid
Middle Aged
Phenotype
Pilot Projects
Receptors, Interleukin-2
Recombinant Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1998596
DOI: 10.1111/j.1365-2141.1991.tb07946.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1998596-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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