Article
Oseltamivir-resistant influenza A pandemic (H1N1) 2009 virus, Hong Kong, China.
Emerging infectious diseases - 1 Dec 2009
Chen Honglin, Cheung Chung Lam, Tai Hung, Zhao Pengxi, Chan Jasper F W, Cheng Vincent C C, Chan Kwok Hung, Yuen Kwok Yung
Abstract excerpt
Resistance to oseltamivir was observed in influenza A pandemic (H1N1) 2009 virus isolated from an untreated person in Hong Kong, China. Investigations showed a resistant virus with the neuraminidase (NA) 274Y genotype in quasi-species from a nasopharyngeal aspirate. Monitoring for the naturally occurring NA 274Y mutation in this virus is necessary.
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