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Article

Influence of DNA repair RAD51 gene variants in overall survival of non-small cell lung cancer patients treated with first line chemotherapy.

Cancer chemotherapy and pharmacology - 1 Aug 2010

Nogueira Augusto, Catarino Raquel, Coelho Ana, Araújo António, Gomes Mónica, Medeiros Rui

Abstract excerpt

PURPOSE: Lung cancer continues to be the most frequent cancer with approximately one million people worldwide dying of this disease each year. Non-small-cell lung cancer (NSCLC) accounts for approximately 80% of all lung cancers. The RAD51 protein is the key protein for homologous recombination, an evolutionarily conserved mechanism for DNA damage repair and the generation of genetic diversity. We conducted this...

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Source

Identifiers

PMID: 19960343
DOI: 10.1007/s00280-009-1187-2

Genes

RAD51

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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