Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel polymorphism causes a different restriction pattern by RsaI in the beta-globin gene cluster: application in prenatal diagnosis.

Hemoglobin - 1 Jan 2009

Valaei Atefeh, Bayat Fatemeh, Kordafshari Alireza, Zeinali Sirous, Karimipoor Morteza

Abstract excerpt

beta-Thalassemia (beta-thal) is a major health problem in Iran and the incidence of carriers is around 3-4%. The disease is caused by heterogeneous mutations in the beta-globin gene and is characterized by hypochromic microcytic anemia. The human beta-globin complex spans a region of 70 kb and contains over 20 restriction fragment length polymorphisms (RFLPs). At least nine RFLP markers including RsaI/beta in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Globins
Share to Deoxyribonucleases, Type II Site-Specific

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Family Health

Share to Hemoglobinopathies

Share to Hemoglobins, Abnormal

Share to Point Mutation

Share to Prenatal Diagnosis

Source

Identifiers

PMID: 19958186
DOI: 10.3109/03630260903327817

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel polymorphism causes a different restriction pattern by RsaI in the beta-globin gene cluster: application in prenatal diagnosis.PMID 19958186Read ↗

Scanning of beta-globin gene for identification of beta-thalassemia mutation in Romanian population.Semantic proximity Read ↗

IVSII-666 of human beta-globin gene: a polymorphic marker linked to codon 8(-AA) mutation.Semantic proximity Read ↗

Beta Globin Gene Cluster Haplotypes in Beta Thalassemia in the Kurdistan Region of Iraq.Semantic proximity Read ↗

Prenatal molecular diagnosis of beta-thalassemia: report on the first two cases in Romania.Semantic proximity Read ↗

Molecular detection of Spanish deltabeta-thalassemia associated with beta-thalassemia identified during prenatal diagnosis.Semantic proximity Read ↗

Detection of nine Mediterranean β-thalassemia mutations in Palestinians using three restriction enzyme digest panels: a reliable method for developing countries.Semantic proximity Read ↗

Screening of Iranian thalassemic families for the most common deletions of the beta-globin gene cluster.Semantic proximity Read ↗

Postnatal and non-invasive prenatal detection of β-thalassemia mutations based on Taqman genotyping assays.Semantic proximity Read ↗

Rapid detection of fetal Mendelian disorders: thalassemia and sickle cell syndromes.Semantic proximity Read ↗

Molecular analysis of beta-thalassemia and sickle cell anemia in Antalya.Semantic proximity Read ↗

Molecular and hematologic analysis of hemoglobin Q-Iran and hemoglobin Setif in Iranian families.Semantic proximity Read ↗

Linkage disequilibrium between a SacI restriction fragment length polymorphism and two galactosemia mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.