Article
Molecular and hematologic analysis of hemoglobin Q-Iran and hemoglobin Setif in Iranian families.
Archives of Iranian medicine - 1 Jul 2008
Rahimi Zohreh, Rezaei Mansour, L Nagel Ronald, Muniz Adriana
Abstract excerpt
BACKGROUND: Single nucleotide mutations in alpha1 or alpha2 genes produce abnormal alpha-chain hemoglobins. Hemoglobin Q disorders including hemoglobin Q-Iran, hemoglobin Q-Thailand, and hemoglobin Q-India are important hemoglobin variants. Herein, we report on the presence and hematologic and molecular features of hemoglobin Q-Iran [alpha75 (EF4) Asp-->His] in 20 members of 11 families including nine children...
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