Linkage disequilibrium between a SacI restriction fragment length polymorphism and two galactosemia mutations.

doi:10.1007/BF00225208

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Article

Linkage disequilibrium between a SacI restriction fragment length polymorphism and two galactosemia mutations.

Human genetics - 1 Mar 1995

Lin H C, Reichardt J K

Abstract excerpt

We have identified a novel SacI restriction fragment length polymorphism (RFLP) in the human galactose-1-phosphate uridyl transferase (GALT) gene. This RFLP can be readily typed by the polymerase chain reaction (PCR). The polymorphic allele is found on about 11% of normal chromosomes and is in li...

Topics

DNA Mutational Analysis
Deoxyribonucleases, Type II Site-Specific
Galactosemias
Humans
Linkage Disequilibrium
Mutation
Polymorphism, Restriction Fragment Length
UTP-Hexose-1-Phosphate Uridylyltransferase

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