Article
Insights into protein aggregation by NMR characterization of insoluble SH3 mutants solubilized in salt-free water.
PloS one - 23 Nov 2009
Liu Jingxian, Song Jianxing
Abstract excerpt
Protein aggregation in vivo has been extensively associated with a large spectrum of human diseases. On the other hand, mechanistic insights into protein aggregation in vitro were incomplete due to the inability in solubilizing insoluble proteins for high-resolution biophysical investigations. Ho...
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