Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CD38/CD31 Interactions Activate Genetic Pathways Leading to Proliferation and Migration in Chronic Lymphocytic Leukemia Cells

20 Nov 2009

Abstract excerpt

Human CD38 is a pleiotropic glycoprotein belonging to a family of enzymes/receptors involved in the catabolism of extracellular nucleotides. CD38-receptor activities are regulated through binding to the nonsubstrate ligand CD31. CD38 expression above a critical threshold is a negative prognostic marker for chronic lymphocytic leukemia (CLL) patients. Activation of CD38 by means of agonistic monoclonal antibodies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium signaling and nucleotide metabolism
Share to Chronic Lymphocytic Leukemia Research
Share to Glycosylation and Glycoproteins Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19956559
DOI: 10.2119/molmed.2009.00146

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CD38/CD31 Interactions Activate Genetic Pathways Leading to Proliferation and Migration in Chronic Lymphocytic Leukemia CellsPMID 19956559Read ↗

In-tandem insight from basic science combined with clinical research: CD38 as both marker and key component of the pathogenetic network underlying chronic lymphocytic leukemiaSemantic proximity Read ↗

CD38 and chronic lymphocytic leukemia: a decade laterSemantic proximity Read ↗

Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevanceSemantic proximity Read ↗

Role of CD38 Expression in Diagnosis and Pathogenesis of Chronic Lymphocytic Leukemia and Its Potential as Therapeutic TargetSemantic proximity Read ↗

The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting.Semantic proximity Read ↗

Role of the human CD38 molecule in B cell activation and proliferation.Semantic proximity Read ↗

CD38 expression labels an activated subset within chronic lymphocytic leukemia clones enriched in proliferating B cellsSemantic proximity Read ↗

CD38 gene polymorphism and chronic lymphocytic leukemia: a role in transformation to Richter syndrome?Semantic proximity Read ↗

CD49d in B-cell chronic lymphocytic leukemia: correlated expression with CD38 and prognostic relevanceSemantic proximity Read ↗

CD38 expression and secondary 17p deletion are important prognostic factors in chronic lymphocytic leukaemiaSemantic proximity Read ↗

p38 in chronic myelogenous leukemia: a target and a possible biomarker.Semantic proximity Read ↗

Human myeloma cells express the CD38 ligand CD31Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.