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Article

Pure progressive amnesia and the APPV717G mutation.

Alzheimer disease and associated disorders - 1 Jan 2000

Knight William D, Ahsan R Laila, Jackson Jessica, Cipolotti Lisa, Warrington Elizabeth K, Fox Nick C, Rossor Martin N

Abstract excerpt

We report an isolated, slowly progressive, pure amnestic phenotype in a 59-year-old member of a family affected by autosomal dominant familial Alzheimer disease. Early-onset Alzheimer disease in this family was associated with a V717G mutation in the amyloid precursor protein gene (APP). Subjecti...

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Identifiers

PMID: 19950418
DOI: 10.1097/wad.0b013e31819cb7f3

Genes

APP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19950418-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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