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Article

Analysis of stromal signatures in the tumor microenvironment of ductal carcinoma in situ.

Breast cancer research and treatment - 1 Sept 2010

Sharma M, Beck A H, Webster J A, Espinosa I, Montgomery K, Varma S, van de Rijn M, Jensen K C, West R B

Abstract excerpt

Recent advances in the study of the tumor microenvironment have revealed significant interaction between tumor cells and their surrounding stroma in model systems. We have previously shown that two distinct stromal signatures derived from a macrophage (CSF1) response and a fibroblastic (DTF-like) response are present in subsets of invasive breast cancers and show a correlation with clinical outcome. In the...

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Share to Carcinoma, Ductal, Breast
Share to Carcinoma, Intraductal, Noninfiltrating

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19949854
DOI: 10.1007/s10549-009-0654-0
PMCID: PMC2976659

Genes

CSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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