An Independent Evaluation of the Validity of a DNA-Based Prognostic Test for Adolescent Idiopathic Scoliosis.

doi:10.2106/JBJS.O.00217

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Article

An Independent Evaluation of the Validity of a DNA-Based Prognostic Test for Adolescent Idiopathic Scoliosis.

The Journal of bone and joint surgery. American volume - 16 Dec 2015

Roye Benjamin D, Wright Margaret L, Matsumoto Hiroko, Yorgova Petya, McCalla Daren, Hyman Joshua E, Roye David P, Shah Suken A, Vitale Michael G

Abstract excerpt

BACKGROUND: ScoliScore is a DNA-based prognostic test, designed and used to help to predict the risk of curve progression in patients with adolescent idiopathic scoliosis. The role of this test in clinical practice remains unclear as the published results of the ScoliScore have not been validated independently. The purpose of this study was to determine if the ScoliScore effectively predicted the risk of curve...

Topics

Adolescent
Braces
DNA
Disease Progression
Female
Follow-Up Studies
Genetic Markers
Humans
Logistic Models
Male
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Predictive Value of Tests

Prognosis

ROC Curve

Retrospective Studies

Risk Assessment

Scoliosis

Severity of Illness Index

Source

Open in PubMed

Identifiers

PMID: 26677232
DOI: 10.2106/JBJS.O.00217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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